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The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
OBJECTIVES: GPR142, which is highly expressed in pancreatic islets, has recently been deorphanized as a receptor for aromatic amino acids; however, its physiological role and pharmacological potential is unclear. METHODS AND RESULTS: We find that GPR142 is expressed not only in β- but also in α-cell...
Shranjeno v:
| izdano v: | Mol Metab |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6323244/ https://ncbi.nlm.nih.gov/pubmed/30472415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.10.012 |
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