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Z-DNA and Z-RNA in human disease

Left-handed Z-DNA/Z-RNA is bound with high affinity by the Zα domain protein family that includes ADAR (a double-stranded RNA editing enzyme), ZBP1 and viral orthologs regulating innate immunity. Loss-of-function mutations in ADAR p150 allow persistent activation of the interferon system by Alu dsRN...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Commun Biol
Päätekijä: Herbert, Alan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323056/
https://ncbi.nlm.nih.gov/pubmed/30729177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0237-x
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