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Suppressing Protein Z-Dependent Inhibition of Factor Xa Improves Coagulation in Hemophilia A

BACKGROUND: Hemostasis requires a balance between pro- and anti-coagulant factors. Hemophiliacs bleed due to a procoagulant deficiency. The targeted reduction in the activity of endogenous anticoagulant pathways is currently being investigated as a means of improving hemostasis in hemophilia. Protei...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Girard, Thomas J., Lasky, Nina M., Grunz, Kristin, Broze, George J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322933/
https://ncbi.nlm.nih.gov/pubmed/30451376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14337
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