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Mechanism of Protein-Z-Mediated Inhibition of Coagulation Factor Xa by Z-Protein-Dependent Inhibitor: A Molecular Dynamic Approach

Protein Z is a plasma protein functioning as a carrier for ZPI. Protein Z also accelerates inhibitory effect of ZPI on factor Xa by 1000-fold. Inhibition of coagulation cascade via FXa by ZPI and other serpins is very important safety factor for normal homeostasis protecting human life against unwan...

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Autors principals: Dayer, Mohammad Reza, Ghayour, Omid, Dayer, Mohammad Saaid
Format: Artigo
Idioma:Inglês
Publicat: International Scholarly Research Network 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320014/
https://ncbi.nlm.nih.gov/pubmed/22536522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/762728
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