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Kinetic Characterization of the Protein Z-dependent Protease Inhibitor Reaction with Blood Coagulation Factor Xa

Protein Z-dependent protease inhibitor (ZPI) is a recently identified member of the serpin superfamily that functions as a cofactor-dependent regulator of blood coagulation factors Xa (FXa) and XIa. Here we show that ZPI and its cofactor, protein Z (PZ), inhibit procoagulant membrane-bound factor Xa...

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Detalhes bibliográficos
Main Authors: Huang, Xin, Swanson, Richard, Broze, George J., Olson, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573075/
https://ncbi.nlm.nih.gov/pubmed/18768472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805214200
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