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Protein Z–dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency
Protein Z (PZ) is a plasma vitamin K–dependent protein that functions as a cofactor to dramatically enhance the inhibition of coagulation factor Xa by the serpin, protein Z–dependent protease inhibitor (ZPI). In vitro, ZPI not only inhibits factor Xa in a calcium ion–, phospholipid-, and PZ-dependen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2384128/ https://ncbi.nlm.nih.gov/pubmed/18344422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-126391 |
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