NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells

We previously reported that among the 37 RING finger protein (RNF) family members, RNF183 mRNA is specifically expressed in the kidney under normal conditions. However, the mechanism supporting its kidney-specific expression pattern remains unclear. In this study, we elucidated the mechanism of the...

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Vydáno v:J Biol Chem
Hlavní autoři: Maeoka, Yujiro, Wu, Yan, Okamoto, Takumi, Kanemoto, Soshi, Guo, Xiao Peng, Saito, Atsushi, Asada, Rie, Matsuhisa, Koji, Masaki, Takao, Imaizumi, Kazunori, Kaneko, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322883/
https://ncbi.nlm.nih.gov/pubmed/30413537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002896
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