NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells

We previously reported that among the 37 RING finger protein (RNF) family members, RNF183 mRNA is specifically expressed in the kidney under normal conditions. However, the mechanism supporting its kidney-specific expression pattern remains unclear. In this study, we elucidated the mechanism of the...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Maeoka, Yujiro, Wu, Yan, Okamoto, Takumi, Kanemoto, Soshi, Guo, Xiao Peng, Saito, Atsushi, Asada, Rie, Matsuhisa, Koji, Masaki, Takao, Imaizumi, Kazunori, Kaneko, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322883/
https://ncbi.nlm.nih.gov/pubmed/30413537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002896
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