KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis

BACKGROUND: Fibroblast-like synoviocytes (FLS) and CCR7(−) effector memory T (T(EM)) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas T(EM) cells proliferate and secrete proinflammatory cytokines, dur...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Tanner, Mark R., Pennington, Michael W., Chauhan, Satendra S., Laragione, Teresina, Gulko, Pércio S., Beeton, Christine
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322314/
https://ncbi.nlm.nih.gov/pubmed/30612588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1783-9
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