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KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis

BACKGROUND: Fibroblast-like synoviocytes (FLS) and CCR7(−) effector memory T (T(EM)) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas T(EM) cells proliferate and secrete proinflammatory cytokines, dur...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Tanner, Mark R., Pennington, Michael W., Chauhan, Satendra S., Laragione, Teresina, Gulko, Pércio S., Beeton, Christine
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322314/
https://ncbi.nlm.nih.gov/pubmed/30612588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1783-9
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