KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis

BACKGROUND: Fibroblast-like synoviocytes (FLS) and CCR7(−) effector memory T (T(EM)) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas T(EM) cells proliferate and secrete proinflammatory cytokines, dur...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Tanner, Mark R., Pennington, Michael W., Chauhan, Satendra S., Laragione, Teresina, Gulko, Pércio S., Beeton, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322314/
https://ncbi.nlm.nih.gov/pubmed/30612588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1783-9
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