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KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis

Fibroblast-like synoviocytes (FLS) play important roles in the pathogenesis of rheumatoid arthritis (RA). Potassium channels have regulatory roles in many cell functions. We have identified the calcium- and voltage-gated KCa1.1 channel (BK, Maxi-K, Slo1, KCNMA1) as the major potassium channel expres...

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Detalhes bibliográficos
Main Authors: Hu, Xueyou, Laragione, Teresina, Sun, Liang, Koshy, Shyny, Jones, Karlie R., Ismailov, Iskander I., Yotnda, Patricia, Horrigan, Frank T., Gulko, Pércio S., Beeton, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281680/
https://ncbi.nlm.nih.gov/pubmed/22074915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312264
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