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KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates rat models of rheumatoid arthritis

OBJECTIVE: Fibroblast-like synoviocytes (FLS) participate in joint inflammation and damage during rheumatoid arthritis (RA) and its animal models. The purpose of this study was to define the importance of KCa1.1 (BK, Maxi-K, Slo1, KCNMA1) channel expression and function in FLS and to establish these...

詳細記述

保存先:
書誌詳細
出版年:Arthritis Rheumatol
主要な著者: Tanner, Mark R., Hu, Xueyou, Huq, Redwan, Tajhya, Rajeev B., Sun, Liang, Khan, Fatima S., Laragione, Teresina, Horrigan, Frank T., Gulko, Pércio S., Beeton, Christine
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280298/
https://ncbi.nlm.nih.gov/pubmed/25252152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38883
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