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Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts

Aging and stress promote senescence, which has intrinsic tumor suppressor functions and extrinsic tumor promoting properties. Therefore, it is of utmost importance to delineate the effects of senescence inducers on the various types of cells that compose the different organs. We show here that prima...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Al-Khalaf, Huda H., Ghebeh, Hazem, Inass, Rabia, Aboussekhra, Abdelilah
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321881/
https://ncbi.nlm.nih.gov/pubmed/30397077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00359-18
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