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Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts

Aging and stress promote senescence, which has intrinsic tumor suppressor functions and extrinsic tumor promoting properties. Therefore, it is of utmost importance to delineate the effects of senescence inducers on the various types of cells that compose the different organs. We show here that prima...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Al-Khalaf, Huda H., Ghebeh, Hazem, Inass, Rabia, Aboussekhra, Abdelilah
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321881/
https://ncbi.nlm.nih.gov/pubmed/30397077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00359-18
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