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The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA-binding Protein AUF1

The development and spread of mammary carcinomas require synergetic interplay between tumor cells and their microenvironment through paracrine secretions, which are still not well defined. We have shown here that interleukin-6 (IL-6), either recombinant or secreted from highly invasive breast cancer...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hendrayani, Siti-Fauziah, Al-Khalaf, Huda H., Aboussekhra, Abdelilah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223303/
https://ncbi.nlm.nih.gov/pubmed/25231991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.594044
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