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ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts

The ATR protein kinase is a master regulator of the cellular responses to DNA damage and replication stresses. Despite these crucial physiological roles, the implication of ATR in human carcinogenesis remains elusive. We have shown here that the ATR level is reduced in most cancer-associated fibrobl...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Al-Ansari, Mysoon M., Aboussekhra, Abdelilah
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205174/
https://ncbi.nlm.nih.gov/pubmed/30410668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26159
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