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p16(INK4A) Represses Breast Stromal Fibroblasts Migration/Invasion and Their VEGF-A-dependent Promotion of Angiogenesis through Akt Inhibition

Stromal fibroblasts, the most abundant and probably the most active cellular component of breast cancer-associated stroma, become active and promote angiogenesis through paracrine effects. However, it still unclear how these processes are regulated. Here, we have shown that down-regulation of the tu...

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Detalhes bibliográficos
Main Authors: Al-Ansari, Mysoon M, Hendrayani, Siti-Fauziah, Tulbah, Asma, Al-Tweigeri, Taher, Shehata, Afaf I, Aboussekhra, Abdelilah
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540951/
https://ncbi.nlm.nih.gov/pubmed/23308058
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