p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts

Cancer-associated fibroblasts (CAFs), the most abundant and probably the most active cellular component of breast cancer-associated stroma, promote carcinogenesis through paracrine effects; however, the molecular basis remains elusive. We have shown here that p16(INK4A) expression is reduced in 83%...

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Détails bibliographiques
Auteurs principaux: Al-Ansari, M M, Hendrayani, S F, Shehata, A I, Aboussekhra, A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679618/
https://ncbi.nlm.nih.gov/pubmed/22751126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.270
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