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p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts
Cancer-associated fibroblasts (CAFs), the most abundant and probably the most active cellular component of breast cancer-associated stroma, promote carcinogenesis through paracrine effects; however, the molecular basis remains elusive. We have shown here that p16(INK4A) expression is reduced in 83%...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679618/ https://ncbi.nlm.nih.gov/pubmed/22751126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.270 |
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