l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury

l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia/reperfusion injury. Ser-PAMAM-Cys effectively sca...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Matsuura, Satoru, Katsumi, Hidemasa, Suzuki, Hiroe, Hirai, Natsuko, Takashima, Rie, Morishita, Masaki, Sakane, Toshiyasu, Yamamoto, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321508/
https://ncbi.nlm.nih.gov/pubmed/30513734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040251
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