l-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier

Effective delivery of drug carriers selectively to the kidney is challenging because of their uptake by the reticuloendothelial system in the liver and spleen, which limits effective treatment of kidney diseases and results in side effects. To address this issue, we synthesized l-serine (Ser)–modifi...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Matsuura, Satoru, Katsumi, Hidemasa, Suzuki, Hiroe, Hirai, Natsuko, Hayashi, Hidetaka, Koshino, Kazuhiro, Higuchi, Takahiro, Yagi, Yusuke, Kimura, Hiroyuki, Sakane, Toshiyasu, Yamamoto, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187148/
https://ncbi.nlm.nih.gov/pubmed/30249662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808168115
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