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l-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier

Effective delivery of drug carriers selectively to the kidney is challenging because of their uptake by the reticuloendothelial system in the liver and spleen, which limits effective treatment of kidney diseases and results in side effects. To address this issue, we synthesized l-serine (Ser)–modifi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Matsuura, Satoru, Katsumi, Hidemasa, Suzuki, Hiroe, Hirai, Natsuko, Hayashi, Hidetaka, Koshino, Kazuhiro, Higuchi, Takahiro, Yagi, Yusuke, Kimura, Hiroyuki, Sakane, Toshiyasu, Yamamoto, Akira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187148/
https://ncbi.nlm.nih.gov/pubmed/30249662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808168115
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