Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein Function

P-glycoprotein (P-gp) effluxes lots of chemotherapeutic agents and leads to multidrug resistance (MDR) in cancer treatments. The development of P-gp inhibitors from natural products provide a potential strategy for the beneficial clinical outcomes. This study aimed to evaluate the effects of the nat...

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Publicado no:Molecules
Main Authors: Chen, Hsiu-Ju, Chung, Yun-Lung, Li, Chia-Ying, Chang, Ying-Tzu, Wang, Charles C. N., Lee, Hsiang-Yen, Lin, Hui-Yi, Hung, Chin-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321030/
https://ncbi.nlm.nih.gov/pubmed/30469543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123055
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