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Tenulin and isotenulin inhibit P-glycoprotein function and overcome multidrug resistance in cancer cells
BACKGROUND: Multidrug resistance (MDR) in cancer is one of the main obstacles in treatment with chemotherapy. Drug efflux through P-glycoprotein is the major mechanism involved in MDR. A potential strategy to provide the best possible clinical outcomes is to develop P-glycoprotein (P-gp) inhibitors...
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| Publicat a: | Phytomedicine |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6421864/ https://ncbi.nlm.nih.gov/pubmed/30668405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phymed.2018.09.008 |
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