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Toward understanding cancer stem cell heterogeneity in the tumor microenvironment

The epithelial–mesenchymal transition (EMT) and cancer stem cell (CSC) formation are two paramount processes driving tumor progression, therapy resistance, and cancer metastasis. Recent experiments show that cells with varying EMT and CSC phenotypes are spatially segregated in the primary tumor. The...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bocci, Federico, Gearhart-Serna, Larisa, Boareto, Marcelo, Ribeiro, Mariana, Ben-Jacob, Eshel, Devi, Gayathri R., Levine, Herbert, Onuchic, José Nelson, Jolly, Mohit Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320545/
https://ncbi.nlm.nih.gov/pubmed/30587589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815345116
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