Toward understanding cancer stem cell heterogeneity in the tumor microenvironment

The epithelial–mesenchymal transition (EMT) and cancer stem cell (CSC) formation are two paramount processes driving tumor progression, therapy resistance, and cancer metastasis. Recent experiments show that cells with varying EMT and CSC phenotypes are spatially segregated in the primary tumor. The...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bocci, Federico, Gearhart-Serna, Larisa, Boareto, Marcelo, Ribeiro, Mariana, Ben-Jacob, Eshel, Devi, Gayathri R., Levine, Herbert, Onuchic, José Nelson, Jolly, Mohit Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320545/
https://ncbi.nlm.nih.gov/pubmed/30587589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815345116
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