Toward understanding cancer stem cell heterogeneity in the tumor microenvironment

The epithelial–mesenchymal transition (EMT) and cancer stem cell (CSC) formation are two paramount processes driving tumor progression, therapy resistance, and cancer metastasis. Recent experiments show that cells with varying EMT and CSC phenotypes are spatially segregated in the primary tumor. The...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Bocci, Federico, Gearhart-Serna, Larisa, Boareto, Marcelo, Ribeiro, Mariana, Ben-Jacob, Eshel, Devi, Gayathri R., Levine, Herbert, Onuchic, José Nelson, Jolly, Mohit Kumar
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320545/
https://ncbi.nlm.nih.gov/pubmed/30587589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815345116
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