MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

Mitochondria are metabolic organelles that are essential for mammalian life, but the dynamics of mitochondrial metabolism within mammalian tissues in vivo remains incompletely understood. While whole-tissue metabolite profiling has been useful for studying metabolism in vivo, such an approach lacks...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Bayraktar, Erol C., Baudrier, Lou, Özerdem, Ceren, Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Cangelosi, Andrew L., Sabatini, David M., Birsoy, Kıvanç, Chen, Walter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320505/
https://ncbi.nlm.nih.gov/pubmed/30541894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816656115
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