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Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits

Bloodborne infections with Candida albicans are an increasingly recognized complication of modern medicine. Here, we present a mouse model of low-grade candidemia to determine the effect of disseminated infection on cerebral function and relevant immune determinants. We show that intravenous injecti...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wu, Yifan, Du, Shuqi, Johnson, Jennifer L., Tung, Hui-Ying, Landers, Cameron T., Liu, Yuwei, Seman, Brittany G., Wheeler, Robert T., Costa-Mattioli, Mauro, Kheradmand, Farrah, Zheng, Hui, Corry, David B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320369/
https://ncbi.nlm.nih.gov/pubmed/30610193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07991-4
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