Selective cleavage of fibrinogen by diverse proteinases initiates innate allergic and antifungal immunity through CD11b

Proteinases are essential drivers of allergic airway disease and innate antifungal immunity in part through their ability cleave the clotting factor fibrinogen (FBG) into fibrinogen cleavage products (FCPs) that signal through Toll-like receptor 4 (TLR4). However, the mechanism by which FCPs engage...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Landers, Cameron T., Tung, Hui-Ying, Knight, J. Morgan, Madison, Matthew C., Wu, Yifan, Zeng, Zhimin, Porter, Paul C., Rodriguez, Antony, Flick, Matthew J., Kheradmand, Farrah, Corry, David B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552423/
https://ncbi.nlm.nih.gov/pubmed/30992366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006724
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