Selective cleavage of fibrinogen by diverse proteinases initiates innate allergic and antifungal immunity through CD11b

Proteinases are essential drivers of allergic airway disease and innate antifungal immunity in part through their ability cleave the clotting factor fibrinogen (FBG) into fibrinogen cleavage products (FCPs) that signal through Toll-like receptor 4 (TLR4). However, the mechanism by which FCPs engage...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Landers, Cameron T., Tung, Hui-Ying, Knight, J. Morgan, Madison, Matthew C., Wu, Yifan, Zeng, Zhimin, Porter, Paul C., Rodriguez, Antony, Flick, Matthew J., Kheradmand, Farrah, Corry, David B.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552423/
https://ncbi.nlm.nih.gov/pubmed/30992366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006724
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires