Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4

Proteinases and the innate immune receptor Toll-like receptor 4 (TLR4) are essential for expression of allergic inflammation and diseases such as asthma. A mechanism that links these inflammatory mediators is essential for explaining the fundamental basis of allergic disease but has been elusive. He...

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Bibliographic Details
Main Authors: Millien, Valentine Ongeri, Lu, Wen, Shaw, Joanne, Yuan, Xiaoyi, Mak, Garbo, Roberts, Luz, Song, Li-Zhen, Knight, J. Morgan, Creighton, Chad J., Luong, Amber, Kheradmand, Farrah, Corry, David B.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898200/
https://ncbi.nlm.nih.gov/pubmed/23950537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240342
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