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Modular Synthesis of Cell-Permeating 2-Ketoglutarate Esters
Cell-permeating esters of 2-ketoglutarate (2-KG) have been synthesized through a convergent sequence from two modules in two and three steps, respectively. This route provides access to a full series of mono- and disubstituted 2-KG esters, enabling us to define the effect of regioisomeric masking on...
Gardado en:
| Publicado en: | Org Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6320255/ https://ncbi.nlm.nih.gov/pubmed/25915096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00737 |
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