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Chemical control of a CRISPR-Cas9 acetyltransferase

Lysine acetyltransferases (KATs) play a critical role in the regulation of transcription and other genomic functions. However, a persistent challenge is the development of assays capable of defining KAT activity directly in living cells. Towards this goal, here we report the application of a previou...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Shrimp, Jonathan H., Grose, Carissa, Widmeyer, Stephanie R. T., Thorpe, Abigail L., Jadhav, Ajit, Meier, Jordan L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320253/
https://ncbi.nlm.nih.gov/pubmed/29309117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00883
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