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Optical Control of CRISPR/Cas9 Gene Editing

The CRISPR/Cas9 system has emerged as an important tool in biomedical research for a wide range of applications, with significant potential for genome engineering and gene therapy. In order to achieve conditional control of the CRISPR/Cas9 system, a genetically encoded light-activated Cas9 was engin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Hemphill, James, Borchardt, Erin K., Brown, Kalyn, Asokan, Aravind, Deiters, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919123/
https://ncbi.nlm.nih.gov/pubmed/25905628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja512664v
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