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Insight into the PTEN – p85α interaction and lipid binding properties of the p85α BH domain
The phosphatidylinositol 3-kinase (PI3K) pathway plays a key role in regulating cell growth and cell survival and is frequently deregulated in cancer cells. p85α regulates the p110α lipid kinase, and also stabilizes and stimulates PTEN, the lipid phosphatase that downregulates this pathway. In this...
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| Yayımlandı: | Oncotarget |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319338/ https://ncbi.nlm.nih.gov/pubmed/30651929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26432 |
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