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Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase
The phosphatidylinositol 3-kinase (PI3K) signaling pathway is deregulated in many human diseases including cancer, diabetes, obesity, and autoimmunity. PI3K consists of a p110 catalytic protein and a p85α regulatory protein, required for the stabilization and localization of p110-PI3K activity. The...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851819/ https://ncbi.nlm.nih.gov/pubmed/20212113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908899107 |
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