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Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4
MLL3 and MLL4 are two closely related members of the SET1/MLL family of histone H3K4 methyltransferases and are responsible for monomethylating histone H3K4 on enhancers, which are essential in regulating cell-type-specific gene expression. Mutations of MLL3 or MLL4 have been reported in different t...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6318328/ https://ncbi.nlm.nih.gov/pubmed/30604749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07906-3 |
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