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Structural mechanisms of selectivity and gating in anion channelrhodopsins
Both designed and natural anion-conducting channelrhodopsins (dACRs and nACRs, respectively) have been widely applied in optogenetics (enabling selective inhibition of target-cell activity during animal behaviour studies), but each class exhibits performance limitations, underscoring trade-offs in c...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317992/ https://ncbi.nlm.nih.gov/pubmed/30158697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0504-5 |
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