Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma

Multiple myeloma (MM) is an incurable hematological malignancy caused by accumulation of abnormal clonal plasma cells. Despite the recent development of novel therapies, relapse of MM eventually occurs as a result of a remaining population of drug‐resistant myeloma stem cells. Side population (SP) c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Nakagawa, Makoto, Fujita, Shuhei, Katsumoto, Takuo, Yamagata, Kazutsune, Ogawara, Yoko, Hattori, Ayuna, Kagiyama, Yuki, Honma, Daisuke, Araki, Kazushi, Inoue, Tatsuya, Kato, Ayako, Inaki, Koichiro, Wada, Chisa, Ono, Yoshimasa, Yamamoto, Masahide, Miura, Osamu, Nakashima, Yasuharu, Kitabayashi, Issay
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317945/
https://ncbi.nlm.nih.gov/pubmed/30343511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13840
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