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Roles of AML1/RUNX1 in T‐cell malignancy induced by loss of p53

AML1 / RUNX1 is a frequent target of chromosome translocations and mutations in myeloid and B‐cell leukemias, and upregulation of AML1 is also observed in some cases of T‐cell leukemias and lymphomas. This study shows that the incidence of thymic lymphoma in p53‐null mice is less frequent in the Aml...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Shimizu, Kimiko, Yamagata, Kazutsune, Kurokawa, Mineo, Mizutani, Shuki, Tsunematsu, Yukiko, Kitabayashi, Issay
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657260/
https://ncbi.nlm.nih.gov/pubmed/23679839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12199
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