Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells

Acute myeloid leukemia is a clonal malignant disorder derived from a small number of leukemic stem cells (LSCs). Rearrangements of the mixed lineage leukemia (MLL) gene are found in acute myeloid leukemia associated with poor prognosis. The upregulation of Hox genes is critical for LSC induction and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Sci
Päätekijät: Aikawa, Yukiko, Yamagata, Kazutsune, Katsumoto, Takuo, Shima, Yutaka, Shino, Mika, Stanley, E Richard, Cleary, Michael L, Akashi, Koichi, Tenen, Daniel G, Kitabayashi, Issay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2015
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373983/
https://ncbi.nlm.nih.gov/pubmed/25529853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12593
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