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PU.1-mediated upregulation of M-CSFR is critical for MOZ-leukemia stem cell potential

Leukemias and other cancers possess self-renewing stem cells that help to maintain the cancer1,2. Cancer stem cell eradication is thought to be critical for successful anti-cancer therapy. Using an acute myeloid leukemia (AML) model induced by introducing the leukemia-associated monocytic leukemia z...

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Bibliographic Details
Main Authors: Aikawa, Yukiko, Katsumoto, Takuo, Zhang, Pu, Shima, Haruko, Shino, Mika, Terui, Kiminori, Ito, Etsuro, Ohno, Hiroaki, Stanley, E. Richard, Singh, Harinder, Tenen, Daniel G, Kitabayashi, Issay
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039870/
https://ncbi.nlm.nih.gov/pubmed/20418886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2122
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