Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases, including multiple sclerosis (MS) and Alzheimer’s disease (AD). However, mechanisms linking blood-brain barrier (BBB) disruption with neurodege...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Immunol
Main Authors: Ryu, Jae Kyu, Rafalski, Victoria A., Meyer-Franke, Anke, Adams, Ryan A., Poda, Suresh B., Coronado, Pamela E. Rios, Pedersen, Lars Østergaard, Menon, Veena, Baeten, Kim M., Sikorski, Shoana L., Bedard, Catherine, Hanspers, Kristina, Bardehle, Sophia, Mendiola, Andrew S., Davalos, Dimitrios, Machado, Michael R., Chan, Justin P., Plastira, Ioanna, Petersen, Mark A., Pfaff, Samuel J., Ang, Kenny K., Hallenbeck, Kenneth K., Syme, Catriona, Hakozaki, Hiroyuki, Ellisman, Mark H., Swanson, Raymond A., Zamvil, Scott S., Arkin, Michelle R., Zorn, Stevin H., Pico, Alexander R., Mucke, Lennart, Freedman, Stephen B., Stavenhagen, Jeffrey B., Nelson, Robert B., Akassoglou, Katerina
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317891/
https://ncbi.nlm.nih.gov/pubmed/30323343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0232-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker