Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease1,2,3

Hypoxia-like tissue alterations, characterized by the upregulation of hypoxia-inducible factor-1α (HIF-1α), have been described in the normal appearing white matter and pre-demyelinating lesions of multiple sclerosis (MS) patients. As HIF-1α regulates the transcription of a wide set of genes involve...

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Vydáno v:eNeuro
Hlavní autoři: Le Moan, Natacha, Baeten, Kim M., Rafalski, Victoria A., Kyu Ryu, Jae, Rios Coronado, Pamela E., Bedard, Catherine, Syme, Catriona, Davalos, Dimitrios, Akassoglou, Katerina
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511492/
https://ncbi.nlm.nih.gov/pubmed/26213713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0050-14.2015
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