C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing

The dynamic process by which nuclear RNAi engages a transcriptionally active target, before the repressive state is stably established, remains largely a mystery. Here, we found that the onset of exogenous dsRNA-induced nuclear RNAi in C. elegans is a transgenerational process, and it requires a put...

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Vydáno v:Cell Rep
Hlavní autoři: Kalinava, Natallia, Ni, Julie Zhouli, Gajic, Zoran, Kim, Matthew, Ushakov, Helen, Gu, Sam Guoping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317888/
https://ncbi.nlm.nih.gov/pubmed/30463021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.086
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