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A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans

BACKGROUND: Environmental stress-induced transgenerational epigenetic effects have been observed in various model organisms and human. The capacity and mechanism of such phenomena are poorly understood. In C. elegans, siRNA mediates transgenerational gene silencing through the germline nuclear RNAi...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Ni, Julie Zhouli, Kalinava, Natallia, Chen, Esteban, Huang, Alex, Trinh, Thi, Gu, Sam Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714518/
https://ncbi.nlm.nih.gov/pubmed/26779286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0052-x
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