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Complex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans

BACKGROUND: Small RNA-guided transcriptional silencing (nuclear RNAi) is fundamental to genome integrity and epigenetic inheritance. Despite recent progress in identifying the capability and genetic requirements for nuclear RNAi in Caenorhabditis elegans, the natural targets and cellular functions o...

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Vydáno v:BMC Genomics
Hlavní autoři: Ni, Julie Zhouli, Chen, Esteban, Gu, Sam Guoping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367959/
https://ncbi.nlm.nih.gov/pubmed/25534009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1157
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