A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans

BACKGROUND: Environmental stress-induced transgenerational epigenetic effects have been observed in various model organisms and human. The capacity and mechanism of such phenomena are poorly understood. In C. elegans, siRNA mediates transgenerational gene silencing through the germline nuclear RNAi...

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Dades bibliogràfiques
Publicat a:Epigenetics Chromatin
Autors principals: Ni, Julie Zhouli, Kalinava, Natallia, Chen, Esteban, Huang, Alex, Trinh, Thi, Gu, Sam Guoping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714518/
https://ncbi.nlm.nih.gov/pubmed/26779286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0052-x
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