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Endogenous Notch Signaling in Adult Kidneys Maintains Segment-Specific Epithelial Cell Types of the Distal Tubules and Collecting Ducts to Ensure Water Homeostasis

BACKGROUND: Notch signaling is required during kidney development for nephron formation and principal cell fate selection within the collecting ducts. Whether Notch signaling is required in the adult kidney to maintain epithelial diversity, or whether its loss can trigger principal cell transdiffere...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Am Soc Nephrol
Κύριοι συγγραφείς: Mukherjee, Malini, deRiso, Jennifer, Otterpohl, Karla, Ratnayake, Ishara, Kota, Divya, Ahrenkiel, Phil, Chandrasekar, Indra, Surendran, Kameswaran
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Nephrology 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317606/
https://ncbi.nlm.nih.gov/pubmed/30514723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018040440
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