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Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression

The distal nephron and collecting duct segments of the mammalian kidney consist of intercalated cell types intermingled among principal cell types. Notch signaling ensures that a sufficient number of cells select a principal instead of an intercalated cell fate. However, the precise mechanisms by wh...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Mukherjee, Malini, DeRiso, Jennifer, Janga, Madhusudhana, Fogarty, Eric, Surendran, Kameswaran
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494575/
https://ncbi.nlm.nih.gov/pubmed/32800756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.08.005
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