EphA3 Pay-Loaded Antibody Therapeutics for the Treatment of Glioblastoma

The EphA3 receptor has recently emerged as a functional tumour-specific therapeutic target in glioblastoma (GBM). EphA3 is significantly elevated in recurrent disease, is most highly expressed on glioma stem cells (GSCs), and has a functional role in maintaining self-renewal and tumourigenesis. An u...

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發表在:Cancers (Basel)
Main Authors: Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen S., Bruce, Zara C., Jamieson, Paul R., Smith, Fiona M., Stringer, Brett W., Carrington, Benjamin, Fuchs, Adrian V., Bell, Craig A., Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer J., Boyd, Andrew W., Day, Bryan W.
格式: Artigo
語言:Inglês
出版: MDPI 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316644/
https://ncbi.nlm.nih.gov/pubmed/30562956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120519
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