EphA3 Pay-Loaded Antibody Therapeutics for the Treatment of Glioblastoma

The EphA3 receptor has recently emerged as a functional tumour-specific therapeutic target in glioblastoma (GBM). EphA3 is significantly elevated in recurrent disease, is most highly expressed on glioma stem cells (GSCs), and has a functional role in maintaining self-renewal and tumourigenesis. An u...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen S., Bruce, Zara C., Jamieson, Paul R., Smith, Fiona M., Stringer, Brett W., Carrington, Benjamin, Fuchs, Adrian V., Bell, Craig A., Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer J., Boyd, Andrew W., Day, Bryan W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316644/
https://ncbi.nlm.nih.gov/pubmed/30562956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120519
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